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M4K2281

Product Specifications

CAS Number

3034840-19-9

Bioactivity

M4K2281 is a potent and selective inhibitor of ALK2 with a half-maximal inhibitory concentration (IC50) of 2 nanomolar. In both biochemical and cellular assays, M4K2281 and M4K2308 demonstrate strong efficacy against ALK2. Moreover, M4K2281 exhibits a brain-to-plasma ratio that ranges from moderate to high.

Smiles

N1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=C3C(=C1)C4=CC=C(C=C4OCC3)N5CCN(C)CC5

Molecular Formula

C27H31N3O4

Molecular Weight

461.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/293082240898826257/T202331

Available Sizes

Curated Selection

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