DS-003
Product Specifications
CAS Number
676489-50-2
Bioactivity
DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.
Smiles
N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC=4C(=NC=C(OC)C34)C=5N=CC=NC5)CC2
Molecular Formula
C27H22N6O3
Molecular Weight
478.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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