CJZ-3

Product Specifications

CAS Number

766508-73-0

Target

P-gp

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Bioactivity

CJZ-3, a derivative of Lomefloxacin, exhibits significant in vitro inhibition of P-gp function. It enhances the intracellular accumulation of Rh123 in a time-dependent manner and markedly reduces Rh123 efflux from cells.

Smiles

FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)N3CCN(CC4=CC=C(Cl)C(Cl)=C4)CC3

Molecular Formula

C24H22Cl2F2N2

Molecular Weight

447.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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