CJZ-3
Product Specifications
CAS Number
766508-73-0
Target
P-gp
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Bioactivity
CJZ-3, a derivative of Lomefloxacin, exhibits significant in vitro inhibition of P-gp function. It enhances the intracellular accumulation of Rh123 in a time-dependent manner and markedly reduces Rh123 efflux from cells.
Smiles
FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)N3CCN(CC4=CC=C(Cl)C(Cl)=C4)CC3
Molecular Formula
C24H22Cl2F2N2
Molecular Weight
447.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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