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N-butyl Lithocholic Acid

Product Specifications

CAS Number

135013-42-2

Target

Endogenous Metabolite

Related Pathways

Metabolism

Bioactivity

N-butyl Lithocholic acid is a derivative of the secondary bile acid lithocholic acid. Lipid nanoparticles containing N-butyl Lithocholic acid and encapsulating mRNA vaccines that express hemagglutinin show reduced cardiotoxicity, splenic, and hepatic toxicity in mice compared to lipid nanoparticles that contain cholesterol.

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C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(OCCCC)=O)C)[H])[H]

Molecular Formula

C28H48O3

Molecular Weight

432.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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