NH2-GG-DSPE

NH2-GG-DSPE is a lipid compound utilized in liposome formulation. Liposomes, having concentric phospholipid bilayer vesicles, are crucial components in constructing drug delivery systems for anti-cancer and anti-infection applications. This compound enables the encapsulation of highly polar water-soluble cargoes within the internal aqueous spaces of liposomes, while lipophilic cargoes can integrate into and become part of the lipid bilayers. NH2-GG-DSPE is particularly effective for delivering antisense oligonucleotides, overcoming challenges such as inefficient cellular uptake and rapid loss in the body.