What is the catalog number for PfCLK3-IN-1?

The catalog number for PfCLK3-IN-1 is T201861.

What sizes are available for PfCLK3-IN-1?

PfCLK3-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PfCLK3-IN-1 come in?

PfCLK3-IN-1 is available in 2 different pack sizes.

Is PfCLK3-IN-1 in stock?

PfCLK3-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PfCLK3-IN-1?

PfCLK3-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for PfCLK3-IN-1?

Estimated delivery time for PfCLK3-IN-1 is approximately 10 business day(s), depending on your location.

PfCLK3-IN-1

Product Specifications

Target

ABC Transporter, Endogenous Metabolite, Parasite

Related Pathways

Microbiology/Virology, Membrane transporter/Ion channel, Metabolism

Bioactivity

PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.