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UMB24

Product Specifications

CAS Number

1033-69-8

Target

Sigma receptor

Related Pathways

GPCR/G Protein

Bioactivity

UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.

Smiles

N=1C=CC=CC1N2CCN(CCC=3C=CC=CC3)CC2

Molecular Formula

C17H21N3

Molecular Weight

267.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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