M4K2308
Product Specifications
CAS Number
3034840-18-8
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
M4K2308, a selective ALK2 ether-linked inhibitor, demonstrates an IC50 of 2 nM and exhibits greater specificity for ALK2 over ALK5, with an IC50 of 224 nM for ALK5. This compound holds potential for research into Diffuse Intrinsic Pontine Glioma (DIPG) .
Smiles
N1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=C3C(=C1)C4=CC=C(C=C4OCC3)N5CCNCC5
Molecular Formula
C26H29N3O4
Molecular Weight
447.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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