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M4K2308

Product Specifications

CAS Number

3034840-18-8

Target

TGF-beta/Smad

Related Pathways

Stem Cells

Bioactivity

M4K2308, a selective ALK2 ether-linked inhibitor, demonstrates an IC50 of 2 nM and exhibits greater specificity for ALK2 over ALK5, with an IC50 of 224 nM for ALK5. This compound holds potential for research into Diffuse Intrinsic Pontine Glioma (DIPG) .

Smiles

N1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=C3C(=C1)C4=CC=C(C=C4OCC3)N5CCNCC5

Molecular Formula

C26H29N3O4

Molecular Weight

447.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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