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RIPK2-IN-6

Product Specifications

CAS Number

2242432-02-4

Target

NF-κB, p38 MAPK, RIP kinase

Related Pathways

NF-κB, MAPK, Apoptosis

Bioactivity

RIPK2-IN-6 (Compound 15a) is an inhibitor of RIPK that specifically targets the phosphorylation of RIPK2, thereby suppressing the NF-κB and MAPK signaling pathways. It has demonstrated anti-inflammatory and anti-fibrotic activities in a mouse model of colitis induced by Dextran sodium sulfate.

Smiles

O=C1C2=C(OC=C2C)C3=CC=C4C=5C3=C1N(C5C(=O)CC4(C)C)CC=6C=CC=CC6

Molecular Formula

C26H21NO3

Molecular Weight

395.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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