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ERK1/2 inhibitor 11

Product Specifications

Target

Apoptosis, Caspase, ERK

Related Pathways

Apoptosis, MAPK, Proteases/Proteasome

Bioactivity

ERK1/2 inhibitor 11 (compound L6) is a dual inhibitor of ERK1/2 that promotes the accumulation of DSBs and the degradation of ERK1/2 expression. This compound decreases BCL-2 levels and induces DNA damage by inhibiting PARP and ERK1/2. Additionally, ERK1/2 inhibitor 11 activates caspase 3 to induce apoptosis.

Smiles

OC1=CC(NC(/C2=N\NC(NN3CCCCCC3)=S)=O)=C2C=C1

Molecular Formula

C15H19N5O2S

Molecular Weight

333.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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