MG-T-19
Product Specifications
CAS Number
328540-44-9
Target
Immunology/Inflammation related
Related Pathways
Immunology/Inflammation
Purity
0.9914
Bioactivity
MG-T-19, a TIM-3 inhibitor (KD=0.26 μM), significantly inhibited the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs, which reactivated the tumor-attacking ability of T cells.
Smiles
O=C(NC1=CC(Cl)=CC=C1O)C2=NN3C(N=C(C=C3C(F)(F)F)C=4SC=C(Br)C4)=C2Br
Molecular Formula
C18H8Br2ClF3N4O2S
Molecular Weight
596.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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