VU6043653
Product Specifications
CAS Number
3032791-06-0
Target
ROCK|||HDAC
Related Pathways
Chromatin/Epigenetic|||Stem Cells|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling
Bioactivity
VU6043653 is an effective, selective, and blood-brain barrier-permeable negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), with an IC50 value of 325 nM against h mGlu5.
Smiles
O=C(NC1=NC=C(F)C=C1)C=2N=C(C=C(OC=3C=NN(C3)C)C2)C
Molecular Formula
C16H14FN5O2
Molecular Weight
327.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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