VU6043653

Product Specifications

CAS Number

3032791-06-0

Target

ROCK|||HDAC

Related Pathways

Chromatin/Epigenetic|||Stem Cells|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling

Bioactivity

VU6043653 is an effective, selective, and blood-brain barrier-permeable negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), with an IC50 value of 325 nM against h mGlu5.

Smiles

O=C(NC1=NC=C(F)C=C1)C=2N=C(C=C(OC=3C=NN(C3)C)C2)C

Molecular Formula

C16H14FN5O2

Molecular Weight

327.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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