GPD-1116
Product Specifications
CAS Number
690690-72-3
Target
Ligand for E3 Ligase, Apoptosis
Related Pathways
PROTAC, Apoptosis
Bioactivity
GPD-1116 is an orally active inhibitor of phosphodiesterase (PDE) 4 and PDE1. The compound effectively reduces smoke-induced apoptosis in lung cells. Additionally, GPD-1116 has shown efficacy in various animal disease models, including emphysema, acute lung injury, chronic obstructive pulmonary disease (COPD), asthma, and pulmonary arterial hypertension.
Smiles
O=C1C=2C(=NNC2C=3C=CC=NC3N1C=4C=CC=CC4)CC=5C=CC=CC5
Molecular Formula
C22H16N4O
Molecular Weight
352.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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