MX69-102
Product Specifications
Target
EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Compound MX69-102 is an MDM-2/p53 inhibitor that promotes MDM2 degradation, resulting in the activation of p53 and the apoptosis of cancer cells. It demonstrates effective inhibition against human MDM2-overexpressing ALL xenograft tumors in SCID mice.
Smiles
O=C(C)C1=CC=CC(NS(C2=CC=C(NC(C3=CC=C(C(C(C)C)=O)C=C3)[C@H]4[C@@H]5OCC4)C5=C2)(=O)=O)=C1
Molecular Formula
C29H30N2O5S
Molecular Weight
518.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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