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JAK1-IN-16

Product Specifications

Target

STAT, Autophagy, JAK, PD-1/PD-L1, AUTACs, TLR

Related Pathways

Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Autophagy, JAK/STAT signaling, Apoptosis, Stem Cells, PROTAC, Angiogenesis, Immunology/Inflammation

Bioactivity

JAK1-IN-16 (compound 4l) acts as an inhibitor of JAK1/STAT3 and effectively downregulates the expression of TLR4 protein.

Smiles

ClC1=C(C(F)(F)F)C=C(NC(CSC2=CC=C(C3=CC=C(C)C=C3)N=N2)=O)C=C1

Molecular Formula

C20H15ClF3N3OS

Molecular Weight

437.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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