AMPK activator 15
Product Specifications
Target
AMPK, E1/E2/E3 Enzyme, Mitochondrial Metabolism
Related Pathways
Ubiquitination, PI3K/Akt/mTOR signaling, Metabolism, Chromatin/Epigenetic
Bioactivity
AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA) -induced lipid accumulation.
Smiles
O=C1OC2=CC(OCC3=CC(OCCCC[P+](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=CC=C3[N+]([O-])=O)=CC=C2C=C1COC(OC7=C(C(C)(C)CC(S)=O)C(C)=CC(C)=C7)=O.[Br-]
Molecular Formula
C53H51BrNO10PS
Molecular Weight
1004.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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