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NOD1-RIPK2-IN-1

Product Specifications

Target

RIP kinase, NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation, Apoptosis, NF-κB

Bioactivity

NOD1-RIPK2-IN-1 (Compound 37) is an inhibitor of the NOD1-RIPK2 signaling pathway, displaying potent IC50 values of 42 nM and 1.52 nM against NOD1 and RIPK2, respectively. This compound effectively reduces the secretion of the pro-inflammatory cytokine IL-8, making it valuable for research in inflammation and immune disorders.

Molecular Formula

C22H26Cl2N4O3

Molecular Weight

465.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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