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SJ46411-Br

Product Specifications

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

SJ46411-Br is an orally effective CK1α molecular glue (Molecular Glue) degrader. It binds with CRL2^KLHDC2 to facilitate the formation of a cooperative homoselective ternary complex. Furthermore, SJ46411-Br is coupled with the BET ligand JQ1 through a PROTAC linker, enabling the synthesis of corresponding PROTACs.

Molecular Formula

C17H13BrN2O3S

Molecular Weight

405.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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