What is the catalog number for TGase2-IN-1?

The catalog number for TGase2-IN-1 is T201596.

What sizes are available for TGase2-IN-1?

TGase2-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TGase2-IN-1 come in?

TGase2-IN-1 is available in 2 different pack sizes.

Is TGase2-IN-1 in stock?

TGase2-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TGase2-IN-1?

TGase2-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for TGase2-IN-1?

Estimated delivery time for TGase2-IN-1 is approximately 10 business day(s), depending on your location.

TGase2-IN-1

Product Specifications

CAS Number

2244702-64-3

Target

Glutaminase, Ligands for Target Protein for PROTAC

Related Pathways

Proteases/Proteasome, PROTAC

Bioactivity

TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 μM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 μM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.