YM-31636 free base
Product Specifications
CAS Number
159081-22-8
Target
5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.
Smiles
N1=CNC(=C1)CC2=NC=3C=4C=CC=CC4CC3S2
Molecular Formula
C14H11N3S
Molecular Weight
253.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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