FXR agonist 9
Product Specifications
CAS Number
2982502-32-7
Target
FXR
Related Pathways
Metabolism
Bioactivity
FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 μM (maximum efficacy of 75.13%) . It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.
Smiles
O=C(O)C=1C=CC=C(C1)NC(=O)C=2C=CC=CC2NC(=O)CCCOC3=CC=C(C=C3)C(C)(C)C
Molecular Formula
C28H30N2O5
Molecular Weight
474.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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