CPD-10
Product Specifications
CAS Number
3055471-57-0
Target
Apoptosis, PROTACs, Glucocorticoid Receptor, CDK
Related Pathways
PROTAC, Endocrinology/Hormones, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb (5807/811) in a dose-dependent manner.
Smiles
O=C(NC1=NN=C(C=C1)N(C)C)C2=CC=C(N=C2NCCCCCCCNC(=O)CN3CCN(C4=CN=C(C=C4)NC=5N=CC6=C(N5)N(C(=O)C(C(=O)C)=C6C)C7CCCC7)CC3)NC
Molecular Formula
C46H61N15O4
Molecular Weight
888.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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