Antiangiogenic agent 7
Product Specifications
CAS Number
2527888-07-7
Target
Apoptosis, Reactive Oxygen Species
Related Pathways
Apoptosis, Metabolism, NF-κB, Immunology/Inflammation
Bioactivity
Antiangiogenic agent 7 (Compound 1) induces apoptosis, elevates Reactive Oxygen Species (Reactive Oxygen Species), and inhibits the intracellular enzyme thioredoxin reductase. It exhibits anticancer activity with IC50 values ranging from 0.08 to 3.5 μM against cervical cancer cells (HeLa), prostate cancer cells (PC-3), and non-small cell lung cancer cells (A549) . Additionally, Antiangiogenic agent 7 suppresses tumor growth in a mouse xenograft model.
Smiles
S=P(C=1C=CC=CC1)(C=2C=CC=CC2)C=3C=CC=C[C-]3[Au+][P]45CN6CN(CN(C6)C4)C5
Molecular Formula
C24H26AuN3P2S
Molecular Weight
647.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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