KRN7000 analog 3
Product Specifications
CAS Number
1384423-78-2
Bioactivity
KRN7000 analog 3 (Compound 14), an α-GalCer analog featuring a 4-phenoxy substituent, acts as an iNKT agonist. This compound induces higher levels of IL-2 cytokine secretion in mNK1.2 cells (ranging from 49.2 to 62.6 ng/mL) compared to α-GalCer (44.1 ng/mL) . KRN7000 analog 3 shows potential for research in anti-tumor agents and vaccine adjuvants.
Smiles
O(C[C@@H]([C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)NC(CCCCCCCCCCC1=CC=C(OC2=CC=CC=C2)C=C1)=O)[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O
Molecular Formula
C47H77NO10
Molecular Weight
816.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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