EGFR/VEGFR2-IN-3
Product Specifications
Target
Apoptosis|||VEGFR|||EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Apoptosis|||Angiogenesis
Bioactivity
EGFR/VEGFR2-IN-3 (compound 9) is an effective inhibitor of EGFR and VEGFR-2, demonstrating IC50 values of 0.129 µM for EGFR, 0.142 µM for VEGFR-2, and 3.428 µM for COX-2. This compound exhibits cytotoxic properties and induces cell apoptosis (apoptosis) as well as cell cycle arrest at the G2/M phase.
Smiles
O=C(NNC(=S)NC1=CC=C(C=C1)C)CSC2=NC=3C=CC=CC3C(=O)N2C4=CC=C(Cl)C=C4
Molecular Formula
C24H20ClN5O2S2
Molecular Weight
510.03
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/274139177807773875/T201562
CAS Number
710972-61-5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6283353-01 0.1 mL
CD5L, NT (CD5L, API6, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha) (MaxLight 550)
Ask
View Details 
MBS6283353-02 5x 0.1 mL
CD5L, NT (CD5L, API6, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha) (MaxLight 550)
Ask
View Details 
GLP2R13-P 100 µg
Human Glucagon like peptide 2 receptor (GLP2R) Control/blocking peptide #3
Ask
View Details