CB-184
Product Specifications
CAS Number
165307-47-1
Target
Apoptosis, Sigma receptor
Related Pathways
GPCR/G Protein, Apoptosis
Bioactivity
CB-184 is a selective ligand for sigma-2 (σ2) receptors, with Ki values of 7436 nM for sigma-1 (σ1) and 13.4 nM for sigma-2 (σ2), and it promotes apoptosis with antitumor activity.
Smiles
O=C\1C[C@@]2(C[C@](/C1=C\C3=CC(Cl)=C(Cl)C=C3)(N(C)CC2)[H])C4=CC(O)=CC=C4
Molecular Formula
C22H21Cl2NO2
Molecular Weight
402.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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