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PROTAC SMARCA2 degrader-29

Product Specifications

Target

PROTACs|||Neurotensin Receptor|||Epigenetic Reader Domain

Related Pathways

GPCR/G Protein|||PROTAC|||Chromatin/Epigenetic

Bioactivity

PROTAC SMARCA2 degrader-29 (Example 87) is a potent PROTAC SMARCA2 (BRM) degrading agent with a DC50 ranging between 10-100 nM (BRM) and over 1 ?M (BRG1, also known as SMARCA2) .

Smiles

OC1=C(C=2C=C3C(C=C(S3)C4CCN(CC4)C5CCN(CC5)C=6C=C([C@H](C(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C9=C(C)N=CS9)=O)C[C@@H](O)C7)C(C)C)ON6)=NN2)C=CC=C1

Molecular Formula

C47H54N8O5S2

Molecular Weight

875.11

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/274139177807773845/T201541

CAS Number

2865193-25-3

Available Sizes

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