BIO-2007817
Product Specifications
Target
PTEN, E1/E2/E3 Enzyme, DNA/RNA Synthesis, Antibacterial
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Microbiology/Virology
Bioactivity
BIO-2007817 is a positive allosteric modulator (PAM) of Parkin, an E3 ubiquitin ligase. This compound enhances the activity of wild-type Parkin, stimulates Parkin's autoubiquitination, and induces the appearance of mono-ubiquitinated forms of Miro1 (a Parkin substrate) with an EC50 of 0.17 μM.
Molecular Formula
C32H36N6O3
Molecular Weight
552.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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