KY-455
Product Specifications
CAS Number
178469-71-1
Target
E3 Ligase Ligand-Linker Conjugate, Acyltransferase
Related Pathways
PROTAC, Metabolism
Bioactivity
KY-455 is a novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. It demonstrates inhibition of ACAT in rabbit intestines, liver, macrophages, and adrenal glands with IC50 values of 0.4, 0.9, 2.9, and 4.1 μmol/L, respectively.
Smiles
O=C(NC1=C(C=C(C2=C1N(CC2)CCCCC)C)C)C(C)(C)C
Molecular Formula
C20H32N2O
Molecular Weight
316.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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