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KY-455

Product Specifications

CAS Number

178469-71-1

Target

E3 Ligase Ligand-Linker Conjugate|||Acyltransferase

Related Pathways

PROTAC|||Metabolism

Bioactivity

KY-455 is a novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. It demonstrates inhibition of ACAT in rabbit intestines, liver, macrophages, and adrenal glands with IC50 values of 0.4, 0.9, 2.9, and 4.1 ?mol/L, respectively.

Smiles

O=C(NC1=C(C=C(C2=C1N(CC2)CCCCC)C)C)C(C)(C)C

Molecular Formula

C20H32N2O

Molecular Weight

316.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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