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EA-B2L

Product Specifications

CAS Number

1354444-72-6

Target

E1/E2/E3 Enzyme|||Ligand for E3 Ligase

Related Pathways

Ubiquitination|||PROTAC

Bioactivity

EA-B2L is an effective degrader of glutathione S-transferase (GSTP) with a DC50 of 48 ?M. It is composed of Ethacrynic acid linked to Boc2Lys. EA-B2L plays a significant role in cancer research.

Smiles

C(C(CC)=C)(=O)C1=C(Cl)C(Cl)=C(OCC(NCCCCCCNC([C@@H](NC(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)=O)C=C1

Molecular Formula

C35H54Cl2N4O8

Molecular Weight

729.73

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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