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NLRP3-IN-57

Product Specifications

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1? levels in THP-1 macrophages induced by LPS+Nigericin.

Smiles

OC1=C(O)C=C(C(C2=C(O)[C@@]3(C/C=C(C)\C)[C@](CC/C=C(C)\C)(C)[C@H](C/C=C(C/C=C/C(OC)(C)C)\C)C[C@@](C3=O)(C/C=C(C)\C)C2=O)=O)C=C1

Molecular Formula

C44H60O7

Molecular Weight

700.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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