NLRP3-IN-57

NOD-like Receptor (NLR)

Immunology/Inflammation

NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1? levels in THP-1 macrophages induced by LPS+Nigericin.

OC1=C(O)C=C(C(C2=C(O)[C@@]3(C/C=C(C)\C)[C@](CC/C=C(C)\C)(C)[C@H](C/C=C(C/C=C/C(OC)(C)C)\C)C[C@@](C3=O)(C/C=C(C)\C)C2=O)=O)C=C1

C44H60O7

700.94

Cool pack

-20°C