DD205-291
Product Specifications
CAS Number
3047066-15-6
Target
PROTACs, GluR
Related Pathways
PROTAC, Neuroscience
Bioactivity
DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.
Smiles
O=C1NC(=O)CCN1C2=CC(=CC=C2Cl)C(=O)N3CCC(CC3)CC4CCN(C5=NC=C(C=C5)C6=NC7=C(N=C6)NC=C7C=8C=NN(C8)CC(F)(F)F)CC4
Molecular Formula
C38H38ClF3N10O3
Molecular Weight
775.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RD-MMP13-p-01 96 Tests
Porcine Matrix Metalloproteinase 13 (MMP13) ELISA Kit
Sign In for Pricing
View Details RD-MMP13-p-02 48 Tests
Porcine Matrix Metalloproteinase 13 (MMP13) ELISA Kit
Sign In for Pricing
View Details 
K2606705 3x 1.0 µg
VAX2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details