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UR-AK49

Product Specifications

CAS Number

902154-32-9

Target

PI3K, Apoptosis, Histamine Receptor, Akt, TRP/TRPV Channel

Related Pathways

PI3K/Akt/mTOR signaling, Membrane transporter/Ion channel, Immunology/Inflammation, Cytoskeletal Signaling, GPCR/G Protein, Neuroscience, Apoptosis

Bioactivity

UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.

Smiles

O=C(NC(=N)NCCCC1=CN=CN1)CCC2CCCCC2

Molecular Formula

C16H27N5O

Molecular Weight

305.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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