SDU-071
Product Specifications
CAS Number
3036109-10-8
Target
Apoptosis|||Epigenetic Reader Domain
Related Pathways
Apoptosis|||Chromatin/Epigenetic
Purity
0.9954
Bioactivity
SDU-071 is an orally active BRD4-p53 inhibitor, inhibiting the proliferation of MDA-MB-231 cells, blocking the interaction between BRD4 and the tumor suppressor p53, downregulating the expression of BRD4-targeted genes, thereby inhibiting cell proliferation, migration, and invasion, and inducing cell cycle arrest and apoptosis. SDU-071 is used for research on triple-negative breast cancer.
Smiles
COC(C=C1)=CC=C1NCC(C=C2NC3=CC=C(OC)C=C3)=NC4=C2C=CC5=C4C=CC=C5
Molecular Formula
C28H25N3O2
Molecular Weight
435.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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