What is the catalog number for JQ dS-4?

The catalog number for JQ dS-4 is T201378.

What sizes are available for JQ dS-4?

JQ dS-4 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does JQ dS-4 come in?

JQ dS-4 is available in 2 different pack sizes.

JQ dS-4 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JQ dS-4?

JQ dS-4 is manufactured by Molfinity.

What is the estimated delivery time for JQ dS-4?

Estimated delivery time for JQ dS-4 is approximately 10 business day(s), depending on your location.

JQ dS-4

Product Specifications

CAS Number

2688882-69-9

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Bioactivity

JQ dS-4 is a degrader of Brahma-related gene 1 (BRG1) /BRM/SMARCA4 (PROTAC®; DC50 range = 9 - 390 nM in glioma models and cell lines), featuring a BRG1 inhibitor connected through a linker to a cereblon (CRBN) E3 ligase ligand. It effectively degrades BRG1 completely over 48 and 72 hours in HSJD-DIPG007 and SU-DIPGXIIIP cells. Additionally, it lessens the viability of various cancer cell lines, including those of H3K27M glioma, prostate, thyroid, and salivary gland.