BAY 593
Product Specifications
CAS Number
2413020-57-0
Target
YAP
Related Pathways
Stem Cells
Bioactivity
BAY 593 functions as an inhibitor of geranylgeranyltransferase-I (GGTase-I), effectively preventing the activation of Rho-GTPases and consequently inactivating YAP1/TAZ signaling pathways. It has been shown to inhibit tumor growth dose-dependently in xenograft mouse models, exhibiting IC50 values of 38.4 nM in MT-1080 cells and 564 nM in MDA-MB-231 cells, as well as in PXF 541 xenografts.
Smiles
O(C)C1=C([C@H]2C3(CCN(C([C@](C(F)(F)F)(OC)C4=CC=CC=C4)=O)CC3)CCNC2)C=CC=C1.Cl
Molecular Formula
C26H32ClF3N2O3
Molecular Weight
512.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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