PDE4-IN-22
Product Specifications
Target
TNF, Interleukin, PDE
Related Pathways
Metabolism, Apoptosis, Immunology/Inflammation
Bioactivity
PDE4-IN-22 (Compound 2e) is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 2.4 nM. It exhibits anti-inflammatory properties and demonstrates significant anti-psoriatic effects in an Imiquimod-induced psoriasis mouse model.
Smiles
[C@@H](NC(=O)C=1N(CC)N=CC1)(C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3CCN(C)CC3)NC(CC)=O)C)C=C2)=O)[C@]4(CC[C@H](C)CC4)[H]
Molecular Formula
C22H19F4N3O3
Molecular Weight
449.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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