EpoY
Product Specifications
CAS Number
245660-13-3
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP) . By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.
Smiles
C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)(=O)[C@@H]2[C@@H](C(OCC)=O)O2
Molecular Formula
C15H17NO7
Molecular Weight
323.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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