MED6-189
Product Specifications
CAS Number
2650073-66-6
Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM) . The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.
Smiles
C(C)(C)[C@@H]1[C@@]2([C@@]([C@](C#N)(C)CC1)(CC[C@](C#N)(C)[C@@H]2O)[H])[H]
Molecular Formula
C17H26N2O
Molecular Weight
274.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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