WRN inhibitor 11
Product Specifications
CAS Number
3058317-61-3
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.
Smiles
O=C(C1=NC=NC(=C1O)C)N2CC3N(C=4C(=O)N5N=C(N=C5N(C4CC)CC(=O)NC6=CC(Cl)=C(C=C6C)C(F)(F)F)C7=CCOCC7)C(C2)CC3
Molecular Formula
C34H35ClF3N9O5
Molecular Weight
742.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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