Antifungal agent 122
Product Specifications
CAS Number
3054212-80-2
Target
Antifungal|||Cytochromes P450
Related Pathways
Metabolism|||Microbiology/Virology
Bioactivity
Antifungalagent 122 (compound 201), a potent and broad-spectrum antifungal agent, prevents the phase shift in fungi and the formation of fungal biofilms. This compound effectively inhibits the enzymatic activity of CYP3A4-M and CYP3A4-T, with IC50 values of 2.11 and 4.53 µM, respectively. Notably, Antifungalagent 122 exhibits no cytotoxicity.
Smiles
[C@](CN1C=NC=N1)([C@H](N(CC2=CC=C(C#CC3=C(F)C=C(F)C=C3)C=C2)C)C)(O)C4=C(F)C=C(F)C=C4
Molecular Formula
C28H24F4N4O
Molecular Weight
508.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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