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LBM22

Product Specifications

Target

CDK|||Apoptosis

Related Pathways

Cell Cycle/Checkpoint|||Apoptosis

Bioactivity

LBM22, a CLK2 inhibitor, exhibits an IC50 value of 3.9 nM. It possesses anti-proliferative properties by inhibiting the phosphorylation of SR proteins. Additionally, LBM22 downregulates the expression of Wnt-related proteins and anti-apoptotic proteins, making it applicable in the study of non-small cell lung cancer.

Smiles

O=C1C2=C(N=C(OC)N1C)N(C(=O)N2C)C

Molecular Formula

C28H22F2N6O2

Molecular Weight

512.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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