LBM22
Product Specifications
Target
CDK|||Apoptosis
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
LBM22, a CLK2 inhibitor, exhibits an IC50 value of 3.9 nM. It possesses anti-proliferative properties by inhibiting the phosphorylation of SR proteins. Additionally, LBM22 downregulates the expression of Wnt-related proteins and anti-apoptotic proteins, making it applicable in the study of non-small cell lung cancer.
Smiles
O=C1C2=C(N=C(OC)N1C)N(C(=O)N2C)C
Molecular Formula
C28H22F2N6O2
Molecular Weight
512.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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