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Tyk2-IN-20

Product Specifications

CAS Number

3058568-08-1

Target

JAK

Related Pathways

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic

Bioactivity

Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.

Smiles

C(#N)[C@@]1(C(=O)N(C[C@H]1C)C=2C=3N(C=C(N2)C4=CN(N=C4)C5CC6(C5)COC6)N=CC3)C7CC7

Molecular Formula

C24H25N7O2

Molecular Weight

443.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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