Tyk2-IN-20
Product Specifications
CAS Number
3058568-08-1
Target
JAK
Related Pathways
JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Stem Cells|||Chromatin/Epigenetic
Bioactivity
Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.
Smiles
C(#N)[C@@]1(C(=O)N(C[C@H]1C)C=2C=3N(C=C(N2)C4=CN(N=C4)C5CC6(C5)COC6)N=CC3)C7CC7
Molecular Formula
C24H25N7O2
Molecular Weight
443.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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